General Consulting
Clinical trial subject matter expertise for sponsors, CROs, and partner consultancies working in CNS therapeutic development worldwide. Deep neuroscience and clinical operations expertise applied to your specific clinical challenge.
Not every engagement fits neatly into endpoint consulting or central rater design. Clinical development in neuroscience presents a wide range of challenges that require specialized knowledge: protocol design considerations for neurological populations, scientific advisory for therapeutic strategy, measurement selection for grant applications, and clinical operations guidance for sites administering complex cognitive or motor assessments.
Led by a clinical trial subject matter expert with deep experience across CNS drug development, our consulting practice provides flexible engagements that draw on years of hands-on experience in clinical measurement, trial design, and regulatory strategy. We serve as an extension of your team, providing the specialized CNS expertise that accelerates your program.
Engagements range from a scientific advisor for a single meeting, to a measurement strategy review for your protocol, to ongoing consultation throughout a development program. We also provide due diligence support for investment decisions. Our work spans the full range of CNS conditions, development phases, and global regulatory jurisdictions.
Frequently Asked Questions
What types of CNS consulting engagements does Cerebral Innovations support?
Engagements range from single-meeting scientific advisory to ongoing program consultation. Common types include protocol design review, measurement strategy assessment, literature reviews, due diligence for investors, grant support, and clinical team training.
How does general consulting differ from endpoint consulting?
Endpoint consulting focuses specifically on endpoint selection, COA/DDT strategy, and digital endpoint integration. General consulting covers broader clinical development challenges including protocol design, scientific advisory, clinical operations, and due diligence.
What CNS therapeutic areas does Cerebral Innovations cover?
Hands-on experience across 40+ CNS clinical trials spanning essential tremor, Parkinson disease, Alzheimer disease, Huntington disease, ALS, epilepsy, psychiatric disorders, and rare neurological conditions. Phases 1 through 4 across five global regulatory jurisdictions.
Does Cerebral Innovations provide due diligence support for investors?
Yes. Technical due diligence for investors evaluating CNS assets, covering endpoint strategy risk, measurement sensitivity, regulatory feasibility across jurisdictions, and competitive positioning relative to existing assessment tools.
Can Cerebral Innovations support grant applications for digital endpoint research?
Yes. We provide measurement methodology sections, power analyses based on published effect sizes, IRB documentation support, and letters of support for investigators proposing NeuroQuantix or FaceWise as study endpoints.
What We Deliver
Protocol Design Support
Review and refine clinical protocols with particular attention to endpoint selection, assessment scheduling, rater requirements, measurement-related eligibility criteria, and multi-site operational considerations.
Scientific Advisory
Expert scientific guidance on CNS clinical measurement, neuropsychological assessment, digital biomarker development, and therapeutic area-specific considerations for sponsors and investors.
Clinical Operations Guidance
Site selection criteria for complex neurological assessments, investigator training requirements, and operational procedures that protect data quality in global multi-site trials.
Literature & Landscape Reviews
Targeted reviews of the clinical measurement landscape for your indication. Identifies available tools, known limitations, competitive positioning, and opportunities for differentiation.
Due Diligence & Investment Support
Technical due diligence for investors evaluating CNS assets. Assessment of endpoint strategy risk, measurement sensitivity, and regulatory feasibility for informed investment decisions.
Partner Consultancy Support
Specialized CNS measurement expertise for other consultancies and CROs who need deep domain knowledge for their client engagements. White-label scientific advisory.
Grant & Proposal Support
Strengthen grant applications and clinical proposals with rigorous measurement methodology sections that demonstrate scientific credibility to reviewers and funding bodies.
Training & Education
Custom training programs for clinical teams on neurological assessment administration, digital endpoint use, and best practices for data quality in CNS trials.
Typical Deliverables
Related Resources
NeuroQuantix Platform
Regulatory-grade digital endpoints for objective motor assessment in your CNS trial.
FaceWise Assessment
Memory consolidation measurement for Alzheimer and cognitive decline trials.
21 CFR Part 11 Compliance
Regulatory-grade data infrastructure with audit trails, CDISC exports, and GxP compatibility.
About Our Team
40+ CNS clinical trials across 5 regulatory jurisdictions.
Need specialized CNS expertise?
Tell us about your clinical challenge. We will find the right engagement model for your stage, indication, and market.
Start the Conversation