Objective DBS outcome measurement and programming optimization
Deep brain stimulation outcomes are typically assessed with clinical rating scales that cannot capture the rapid, continuous motor changes that occur during programming. NeuroQuantix enables objective, real-time motor assessment for DBS outcome studies and programming optimization.
The DBS Assessment Challenge
DBS programming involves systematic adjustment of stimulation parameters while observing motor response. Traditional clinical scales cannot capture the rapid, subtle motor changes that distinguish optimal from suboptimal settings. Additionally, long-term DBS outcome studies require sensitive longitudinal tracking that ordinal scales may not detect.
Clinical Applications
Published Evidence
Evidence from peer-reviewed publications supporting digital kinematic endpoints for deep brain stimulation assessment.
DBS On/Off Discrimination
Published validation demonstrates that RMSE and degree of smoothness metrics discriminate DBS on vs. off states, providing objective confirmation of stimulation efficacy.
Pullman SL, et al. Clinical Neurology & Neurosurgery, 2021. DOI: 10.1016/j.clineuro.2021.106878
Programming Optimization
Real-time kinematic analysis during DBS programming sessions enables objective comparison of stimulation parameters, reducing programming time and improving outcomes.
Published DBS assessment literature
Longitudinal Tracking
High test-retest reliability enables detection of gradual motor changes over months to years — critical for long-term DBS outcome studies and adaptive programming.
Published reliability data across conditions
Statistical Power Advantage
Higher measurement precision translates directly into smaller enrollment requirements. See the full interactive power curve comparison on our product page.
View Power VisualizationReady to discuss deep brain stimulation endpoints?
Schedule a consultation to explore how precision digital endpoints can strengthen your deep brain stimulation clinical program.